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Thursday, February 03, 2005

Melanopsin Gene Turns On Eye Cells 

Researchers at the Imperial College London and the University of Manchester have found that nerve cells in the eye will respond to light when the melanpsin gene in those cells is activated:

Using mouse cells, the researchers found that melanopsin could be used to make neurones light responsive. They found that as well as being sensitive to blue light, melanopsin uses light at different wavelengths to regenerate itself. In some forms of hereditary blindness photoreceptors are lost entirely, but the retinal ganglion cells, the cells which signal to the brain, remain intact. The researchers believe that by activating the melanopsin, these cells may gain the ability to sense and respond to light.
'Researchers discover way to make cells in the eye sensitive to light' (Imperial College Press Release at EurekAlert January 2005).

The research was published in the January 26 issue of Nature and will now be used in collabortive work on a retinal prosthesis.

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